Langerhans Cell Histiocytosis in Children: Literature Review
نویسندگان
چکیده
Relevant information on Langerhans cell histiocytosis development and course in children is presented. The current concepts of disease pathogenesis, principles its severity evaluation, patients stratification into risk groups, as well clinical features are described. Modern approaches to the treatment via targeted therapy summarized analyzed.
منابع مشابه
Langerhans cell histiocytosis
Introduction: Langerhans cell histiocytosis (LCH), which was previously known as histiocytosis X, refers to a group of lesions that stimulate uncontrolled proliferation of cells. The purpose of this case was to report and describe a LCH case with mandibular bone involvement in a 2.5-year-old boy. Case reports: A 2.5 years old boy with LCH of mandibular jaw who has been treated by surgical inter...
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Langerhans cell histiocytosis (LCH) is a rare disorder described as three different entities including eosinophilic granulomaof bone, the Hand-Schuller-Christian syndrome, and Letterer-Siwe disease. LCH is currently classified into singlesystem LCH, and multisystem LCH. Patients with single system LCH have an excellent prognosis, and are mostlytreated with local therapy. Multisystem LCH is subd...
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L angerhans’ cell histiocytosis (LCH), formerly known as histiocytosis X, is one of a group of poorly understood diseases of histiocytes. The clinical spectrum of disease ranges from the chronic, localized form to an acute leukemia-like disease with a fatal outcome. Alfred Hand was the first to report a case of histiocytosis in 1893.1 Later, in 1941, Farber described this condition when reporti...
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ژورنال
عنوان ژورنال: Voprosy sovremennoj pediatrii
سال: 2023
ISSN: ['1682-5535', '1682-5527']
DOI: https://doi.org/10.15690/vsp.v22i1.2520